PLINEST® Injectables

PLINEST® is a Polynucleotide Highly Purified Technology (PN-HPT) injectable treatment that restores skin rigidity and elasticity by improving the overall skin health and promoting the production of fibroblast and collagen. It is developed by Mastelli Srl Italy, based on trout gonad DNA.

PLINEST® is a Class III medical device and CE certified. It is the result of 70 years of research, and 100+ published clinical studies and has been used for many decades for skin pathologies (skin aging & damage) treatments.

PLINEST® is clinically proven to improve the overall skin health from deep within the dermal layer by promoting bio-revitalization to reverse signs of aging and regenerating fibroblast and collagen to repair damaged skin.

Thanks to the polynucleotides and hyaluronic acid, each treatment helps to improve hydration and elasticity, as well as boost skin rejuvenation effects for smooth, flawless, and radiant skin. The perfect all-in-one “glow me up” treatment!

Naturally restore, with Italian Trout Fish DNA

PN-HPT™ (Polynucleotide – Highly Purified Technology) is a DNA fragment extracted from Italian Trout Fish using HPT™ technology developed and patented by Mastelli Aesthetic, Italy. With 70 years’ worth of research, the perfected HPT™ technology delivers the highest purification levels of PN.

The perfected formulation assures superior efficacy and safety in compliance even with the highest pharmaceutical standards. The entire manufacturing process from the selection of the best fish to the finished product is closely monitored and controlled by Mastelli Aesthetic in Italy.

Glowing younger with PLINEST®

DNA fragments extracted from Italian Trout Fish using HPT reduces open pores, acne scars, and fine lines. It promotes skin bio-revitalization and collagen restoration through a natural physiological process.

Patients treated with PLINEST® will have better skin radiance, youthful-looking textures, have better skin elasticity, making them look young and healthy. It erases signs of aging of the face and body and is also a good companion to other aesthetic treatments.