PLINEST® Injectables

A Class III medical device and CE certified, PLINEST® is the result of 70 years of research, and 100+ published clinical studies and has been used for many decades for skin pathologies (skin ageing & damage) treatments.

What is PLINEST® Injectables and how does it work?

PLINEST® is a Polynucleotide Highly Purified Technology (PN-HPT) injectable treatment that restores skin rigidity and elasticity by improving the overall skin health and promoting the production of fibroblast and collagen. It is developed by Mastelli Srl Italy, based on trout gonad DNA.

PLINEST® is a Class III medical device and CE certified. It is the result of 70 years of research, and 100+ published clinical studies and has been used for many decades for skin pathologies (skin aging & damage) treatments.

PLINEST® is clinically proven to improve the overall skin health from deep within the dermal layer by promoting bio-revitalisation to reverse signs of aging and regenerating fibroblast and collagen to repair damaged skin.

Thanks to the polynucleotides and hyaluronic acid, each treatment helps to improve hydration and elasticity, as well as boost skin rejuvenation effects for smooth, flawless, and radiant skin. The perfect all-in-one “glow me up” treatment!

Skin Concerns Treated

Dark eye circles

Dull skin

Enlarged pores

Wrinkles and fine lines

Skin sagging

Acne scars

Stretch Marks

Naturally restore, with Italian Trout Fish DNA

PN-HPT™ (Polynucleotide – Highly Purified Technology) is a groundbreaking skin-rejuvenation ingredient, crafted from the DNA of premium Italian trout using patented HPT™ technology by Mastelli Aesthetic, Italy. Backed by 70 years of dedicated research, this advanced technology ensures unmatched purity and quality for your skin.

With a perfected formulation, PN-HPT™ offers superior safety and efficacy, meeting the highest pharmaceutical standards for your peace of mind. From selecting the finest fish to delivering the finished product, every step of the process is meticulously monitored in Italy by Mastelli Aesthetic, ensuring you receive only the best for your skin.

Rejuvenate with the assurance of science, care, and excellence in every drop of PN-HPT™.

Glowing younger with PLINEST®

DNA fragments extracted from Italian Trout Fish using HPT reduces open pores, acne scars, and fine lines. It promotes skin bio-revitalisation and collagen restoration through a natural physiological process.

Patients treated with PLINEST® will have better skin radiance, youthful-looking textures, have better skin elasticity, making them look young and healthy. It erases signs of aging of the face and body and is also a good companion to other aesthetic treatments.

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